Latest Advances in Lung Cancer Research

A major Australian-Canadian lung cancer screening study found that 73% of high-risk participants had incidental findings during baseline CT scans, with 10% requiring clinical follow-up, highlighting significant inconsistencies in how these findings are reported to doctors and raising important questions about standardization as Australia prepares to launch its national screening program in 2025.

Leading lung cancer specialists discuss revolutionary advances in treating EGFR-mutated non-small cell lung cancer, highlighting how new combination therapies like amivantamab plus chemotherapy are doubling progression-free survival and offering hope for patients with challenging complications like leptomeningeal metastases, while emphasizing practical strategies for managing treatment side effects in community practice.

A new JAMA review shows that small cell lung cancer, which affects 95% smokers and has only 12-30% five-year survival, is seeing breakthrough improvements with immunotherapy extending survival to 56 months for early-stage disease, though advanced cases remain challenging with most patients relapsing within three months.

Increasing lung cancer cases in non-smokers highlight the need for research into causes and improved detection methods

Scientists begin first-ever lung cancer vaccine trials in seven countries. The vaccine aims to prevent cancer in high-risk individuals by boosting immune response. Researchers hope it saves lives.

Actress and comedian Kate Micucci, revealed last month that she had been diagnosed and treated for lung cancer despite having “never” smoked cigarettes. Micucci’s diagnosis came as a surprise to her followers, especially considering she is a non-smoker. However, lung cancer among non-smokers happens more often than most people realize.

Changing the current lung cancer guidelines to a 2-year smoking duration cutoff vs a 20 pack-year cutoff would significantly improve the rate of cancer detection and reduce racial disparities with screenings.

Scientists uncover link between car fumes and lung cancer that helps explain why so many non-smokers develop disease.

Studies show smoking marijuana may harm lungs but lacks strong evidence linking it to lung cancer; research is challenged by marijuana’s legal history and variability.

Global lung cancer rates have risen over 30 years with significant regional variations; researchers urge tailored interventions to address this persisting major health issue.

American Cancer Society report shows lung cancer deaths decline, boosting overall cancer survival despite persistent disparities and need for better screening.